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Geniposide promotes phosphorylation of brain-derived neurotrophic factor and cAMP response element-binding protein (CREB) by enhancing cholinergic effects, thereby providing neuroprotection ( Therefore, by regulating oxidation, inflammation, apoptosis, and autophagy, these natural products collectively exert neuroprotective and neurotrophic effects, providing a promising treatment for neurodegenerative diseases and injuries

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No formal half-life measurement has been published

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